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Foods to avoid while taking metformin? While taking metformin, it's wise to avoid certain foods that may exacerbate gastrointestinal issues, including spicy foods, high-fat items, and excessive alcohol. Opt for a balanced diet rich in fiber and nutrients to support your health while on this medication. If you're experiencing the sensation of something stuck in your throat, try sipping warm water, gargling with salt water, or consuming soft foods to ease discomfort and promote swallowing.